Name | Jujuboside B |
Synonyms | Jujuboside Jujuboside B JUJUBOSIDE B xylopyranosyl-(1→2)-β-D-glucopyranosyl-(1→3)]- |
CAS | 55466-05-2 |
InChI | InChI=1/C52H84O21/c1-22(2)15-52-20-50(8,63)42-24-9-10-30-48(6,25(24)16-51(42,73-52)21-66-52)13-11-29-47(4,5)31(12-14-49(29,30)7)69-45-41(72-44-38(62)35(59)32(56)23(3)67-44)39(27(55)19-65-45)70-46-40(36(60)34(58)28(17-53)68-46)71-43-37(61)33(57)26(54)18-64-43/h15,23-46,53-63H,9-14,16-21H2,1-8H3/t23-,24?,25?,26-,27-,28-,29+,30-,31+,32+,33+,34-,35-,36+,37-,38-,39-,40-,41-,42+,43+,44+,45+,46+,48+,49?,50+,51-,52+/m1/s1 |
Molecular Formula | C52H84O21 |
Molar Mass | 1045.21 |
Density | 1.44 |
Melting Point | 228-231°C |
Specific Rotation(α) | -45.2°(c=1.00,methanol) |
Solubility | Easily soluble in methanol, almost insoluble in ether |
Appearance | Colorless needle crystal (methanol) |
pKa | 12.84±0.70(Predicted) |
Storage Condition | 2-8℃ |
Sensitive | Easily absorbing moisture |
Refractive Index | 1.627 |
MDL | MFCD03427710 |
Physical and Chemical Properties | White crystalline powder, soluble in methanol, almost insoluble in ether, derived from Semen Ziziphi Spinosae. |
Safety Description | 24/25 - Avoid contact with skin and eyes. |
HS Code | 29329990 |
Reference Show more | 1. Liu aipeng, Zheng Yuguang, Wen zishuai, etc. Comprehensive evaluation of the effect of Microwave processing on the quality of semen ziziphi spinosae based on analytic hierarchy process and multi-index [J]. Chinese herbal medicines, 2018, 041(001):84-88. 2. Zhu Hongyan, Zhang, na, Tang, Shan, et al. Determination of sinopinoside and ziziphi spinosae saponin A B in semen ziziphi spinosae from three different regions by HPLC [J]. Journal of Pharmaceutical Analysis, 2015 035(012):2099-2104. 3. Lin Haicheng, Zhu Hongyan, He Zhongmei, etc. Optimization of extraction technology of total saponins from semen ziziphi spinosae by orthogonal test [J]. Chinese Journal of Experimental prescriptions, 2015, 21(5):42-45. 4. Zhu Hongyan, Zhang Na, Wang Guoli, Jiang ran, he Zhongmei, Zhang Lianxue. Simultaneous determination of ginsenoside Rg_1, Re, Rb_1 and jujuboside A, B in renshen jianpi pills by HPLC [J]. Chinese Pharmaceutical Journal, 2016,51(09):751-756. 5. Liao Mei, Xu Yao, Lan Jinshan. Simultaneous determination of wild jujube seed saponin A, wild jujube seed saponin B and spinoxin in Lily jujube seed bag tea by HPLC-MS method [J]. China modern distance education of traditional Chinese medicine, 2021,19(03):143-146. 6. [IF = 5.81] Ji Zaixiong et al., and Migration via Activation of AMPK/PPAR-γ Signaling."Front Pharmacol. 2021 Jun;0:1360 7. [IF=2.408] Fang-Tong Li et al."In Vitro Effects of Ginseng and the Seed of Zizyphus jujuba var. spinosa on Gut Microbiota of Rats with Spleen Deficiency."Chem Biodivers. 2020 Sep;17(9):e2000199 |
biological activity | Jujuboside B is an active ingredient extracted from Zizyphus jujuba, which can inhibit platelet aggregation. |
chemical properties | white crystalline powder, soluble in methanol, almost insoluble in ether, derived from jujube seed. |
use | jujube saponin B has the functions of nourishing heart and calming mind, calming and hypnotizing, anti-arrhythmia and anti-myocardial ischemia. used for content determination/identification/pharmacological experiment, etc. Pharmacological effect: anti-sweet activity. 1mM aqueous solution can completely inhibit the sweetness of 0.2M sucrose. |